Career

If you’re inspired by the possibilities of science to improve the treatment of cancer patients and you are interested in personalized cancer vaccine development – join us.

 

TREOS BIO is a UK biotech company with subsidiaries in Budapest and San Francisco. In Budapest you’ll have the opportunity to develop cancer vaccines and deliver these life-changing products to patients in need.

 

We’re pioneering the translational science of personalized immunotherapy, which is one of the most innovative medicine in oncology. We offer the most exiting environment for daily work and a unique and strong collaborative network as part of TREOS BIO family. We want to attract top minds, and we nurture and build top talent.

Medical Director at TREOS BIO Zrt, Budapest, Hungary

Cancer Vaccine Development

Under the leadership of the Chief Medical Officer, leads the direction, planning, execution, and interpretation of clinical programs. Participates in and may lead cross-functional teams to generate, deliver, and disseminate high-quality clinical data supporting overall product scientific and business strategy.

 

Responsibilities:

 

  • Leads the design and implementation of clinical development programs in support of the overall product development plan, based on strong medical and scientific principles, knowledge of compliance and regulatory requirements
  • Has responsibility for mentoring clinical study teams, monitoring study integrity, and review, interpretation, and communication of data pertaining to safety and efficacy of our products
  • Under the supervision of the Chief Medical Officer, has primary responsibility for design, analysis, interpretation, and reporting of scientific content of protocols, Investigator Brochures, Clinical Study reports, regulatory submissions and responses
  • May chair Clinical Strategy Teams, with responsibility for development of a Clinical Development Plan with full consideration of contingencies and alternative approaches
  • Serves as the in-house clinical expert for oncology & immunology, coordinating and leading scientific activities with internal stakeholders as they relate to ongoing projects
  • May represent Company at key external meetings, stays abreast of professional information and technology through conferences, medical literature, and other available training, to augment expertise in the therapeutic area
  • Ensures adherence to Good Clinical Practices, pharmacovigilance standards, standard operating procedures and to all other quality standards in conducting research

 

Qualifications:

 

  • Medical Doctor (M.D.) degree with relevant therapeutic specialty in oncology or immunology in an academic or hospital environment
  • At least 3 years of clinical trial experience
  • Extensive knowledge of clinical trial methodology, regulatory and compliance requirements governing clinical trials, and experience in development of clinical strategy and the design of study protocols
  • Ability to run a complex clinical research program independently
  • Proven leadership skills and ability to bring out the best in others on a cross-functional global team
  • Ability to interact externally and internally to support a global scientific and business strategy
Quality Assurance Manager at TREOS BIO Zrt, Budapest, Hungary

Cancer Vaccine Development

Under the leadership of the Head of Product Development, leads the preparation and maintaining the regulatory documentation and the quality system.

 

Responsibilities:

 

  • Responsible for Regulatory and Compliance support for vaccine and companion diagnostics development
  • Responsible for the coordination and preparation of document packages for regulatory submissions.
  • Provide QA support in the development, manufacturing and release of drug substance and drug product.
  • Maintain and enhance an effective Quality Management System
  • Ensure the proper designation and monitoring of storage conditions for materials and products.
  • Oversee QA Review of process development and transfer protocols, batch records from CMOs as assigned. Work with internal and CMO entities to resolve review comments to acceptance by both Treos Bio and CMO.
  • Provide effective QA support for the manufacturing and disposition of clinical and commercial lots.
  • Recommends changes to labeling, manufacturing, marketing, and clinical and development protocols
  • Oversees the collection of documents, reports, records and data from Development, Clinical Affairs, Quality and Operations Department for inclusion in regulatory documents.
  • Ensure that regulatory documentation is backed up and archived appropriately.
  • Ensure that Document Control activities are compliant with FDA, EU and other applicable requirements and that controlled documents are maintained in an orderly manner to allow rapid retrieval when required.
  • Stay informed regarding industry trends, interpretation of regulations and application

 

Qualifications:

 

  • Pharmacist degree or comparable experience.
  • Effective verbal and written communication with English proficiency and strong organizational skills
  • Knowledge of cGMP, GLP, ICH, and USP regulations or guidelines apply them to both manufacturing and lab environments supporting development work
  • At least 3 years of experience at an operational level in a pharmaceutical or biotech environment.
  • Good understanding of the pharmaceutical industry and it’s regulations
  • Experience in managing US or EU regulatory filing
  • Experience with peptide synthesis, formulation and process development is a plus!
Data Scientist at TREOS BIO Zrt, Budapest, Hungary

Cancer Vaccine Development

Under the leadership of the Head of Bioinformatics, preparation and maintaining the regulatory documentation and the quality system.

 

Responsibilities:

 

  • Manage corporate IT infrastructure, IT operations and IT helpdesk
  • Manage execution and development of policies and procedures including testing, change control, data security and general system maintenance
  • Support the Bioinformatics team developing and upgrading software tools and user interfaces for data upload, cleansing, analysis and retrieval
  • Support the Bioinformatics team on statistical programming tasks, clinical trial databases, filing support and validation of software products

 

Qualifications:

 

  • MSc degree in information technology or a related a technical field.
  • Experience in managing IT operations
  • Ability to apply IT knowledge to new scientific and operational challenges.
  • Familiarity with industry standards such as CDISC, CDASH, SDTM, and ADaM, and programming languages such as Base SAS, SAS/STAT, SAS Macro language and SAS/GRAPH.
  • Effective verbal and written communication with English proficiency and strong interpersonal skills.